Summary
The Mercedes-Benz E350 has 5 recalls spanning 2007 through 2016, with the most serious recent issue affecting 2014-2016 models where the electric power steering control unit can lose connection and drop all steering assist, making the vehicle significantly harder to steer and raising the risk of a crash.
The 2014 model year sedan also has a fuel line recall covering a narrow production window where the fuel feed line was built with an incorrect single-flare fitting instead of a double-flare. That fitting can develop a leak or separate entirely, spilling fuel near the engine. A separate 2014 recall covers certain vehicles that may have received incorrect software during a prior service visit, which can cause loss of drive power, reduced exterior lighting, or failure of stability and traction control.
The 2012 model year, specifically coupe and cabriolet body styles originally sold or registered in high-humidity states including Florida, Hawaii, and several Gulf Coast states, has a Takata-related passenger-side airbag inflator recall. In these vehicles, the inflator can rupture and send metal fragments into the cabin, with the potential for serious injury or death.
Going back to earlier production, 2007-2009 E350 4Matic Wagon models have a rear suspension connecting rod tied to the load-leveling system that can fail, reducing the driver's ability to control the vehicle.
