The 2007 Mercedes-Benz E350 has 5 recalls, the most widespread being a sunroof glass panel that can lose its bond to the sliding roof frame, detach while driving, and become a road hazard for other vehicles.
The sunroof issue covers multiple filings across a broad range of model years, but the underlying problem is the same: the glass panel is not properly secured and can separate from the vehicle at speed. Because this appears across several campaigns targeting overlapping vehicle populations, owners should verify their specific VIN has been remedied, as prior repair attempts may not have fully resolved the issue for all affected vehicles.
On the suspension side, this recall applies only to E350 4MATIC Wagon models. A connecting rod in the load-leveling rear suspension system can fail, which removes the system's ability to maintain proper ride height and can reduce the driver's control of the vehicle, raising the risk of a crash.