The 2021 Audi S5 has 5 recalls, the most serious involving a rear axle lock nut that can break and misalign the rear axle, causing the driver to lose control of the vehicle. A related recall covers the same rear axle misalignment causing premature or uneven tire wear, which can also raise crash risk. On the Sportback body style, the wiring harness for the rear lights may lack abrasion protection near the spare wheel well, so a rear collision can damage the wires and disable the hazard lights and exterior door releases, trapping occupants inside. There is also a rear seatbelt retractor concern where a child restraint system may not be properly secured, reducing protection for young passengers in a crash. The rearview camera on certain vehicles can go blank while reversing, cutting off the driver's view of what is behind the car.